Keller Sophia¹, Braun Lukas², Fischer Emma³, Wagner Elias⁴, Müller Clara⁵, Becker Noah⁶, Vogel Anna⁷, Schmidt Leon⁸
ABSTRACT:
This review explores the emerging role of gut microbiota-derived biomarkers in the context of autoimmune and inflammatory disorders. We analyze the mechanistic links between microbial dysbiosis and immune dysregulation, focusing on key metabolic and immunologic biomarkers such as short-chain fatty acids, lipopolysaccharides, and microbial antigens. Advances in multi-omics platforms, microbial signatures, and their application in disease prediction, diagnosis, and treatment personalization are also discussed. The integration of microbiome-based biomarkers into clinical frameworks may improve early detection, monitoring, and precision interventions in autoimmune pathologies.