Investigation of the expression of antioxidant activity proteins such as SOD1 in cardiac tissues in hyperlipidaemia

Hyperlipidaemia, characterized by elevated levels of lipids in the blood, is a key risk factor for the development of cardiovascular diseases. One of the main mechanisms by which hyperlipidaemia exerts its harmful effects is through oxidative stress, which is caused by an imbalance between the production of reactive oxygen species (ROS) and the antioxidant defense systems. Superoxide dismutase 1 (SOD1) is a critical antioxidant enzyme responsible for neutralizing superoxide radicals, one of the primary ROS in cells. This study investigates the expression of SOD1 in cardiac tissues under conditions of hyperlipidaemia. Using a Western blot approach, we analyze the expression levels of SOD1 in the myocardium of hyperlipidaemic animal models.