Tereshchenko Eva¹, Zharikova Kseniia², Shlyakhov Andrey³, Kanygina Polina⁴, Grigoreva Elizaveta⁵, Tormozakova Evgeniya⁶, Gnedkova Mariya⁷, Savinova Elizaveta⁸, Liang Chen9
ABSTRACT:
Oncology has undergone dramatic transformations in the last few decades, primarily due to advancements in molecular biology, genomics, and therapeutic strategies. These developments are leading to a new era in cancer treatment characterized by precision medicine, targeted therapies, and immunotherapies. The discovery of novel biomarkers and the understanding of the tumor microenvironment have opened new frontiers in both the diagnosis and treatment of cancer. The evolution of immunotherapy, CAR-T cell therapy, and precision oncology has radically altered therapeutic approaches, offering more personalized and less toxic treatments. While these breakthroughs have resulted in remarkable clinical outcomes for certain cancer types, challenges remain, particularly regarding resistance to treatment and the applicability of these therapies to a broader range of cancers. This review aims to explore the molecular and therapeutic advances shaping modern oncology, the current landscape of cancer treatments, and the future directions of cancer care.
