Role of Neuroplasticity in Treating Traumatic Brain Injuries

Bondarenko Xenia1, Anastasia Al-Mutawakel2, Sharkova Anna3, Denisova Olga4, Gasanov Ramazan5, Angliiskaia Irina6, Chadaeva Ulyana7, Kolosova Maria8, Liu Xin9

ABSTRACT:

A Traumatic Brain Injury (TBI) is an injury that poses a major problem to international health. Its damages are of a great concern as it comes with long lasting health implications which can deteriorate the affected person’s quality of life. Recovery from TBI is very difficult, even with the most advanced medical treatment, regaining cognitive, motor and emotional functions is particularly difficult. The extent of brain rehabilitation possible after TBI depends greatly on neuroplasticity, the ability of the brain to reorganize itself by forming new neural connections. This paper seeks to study the reason of TBIs in context of neuroplasticity focusing on the principles of neuroplastic recovery, recovery potential, therapeutic strategies to promote the processes and the mechanisms of neuroplasticity. The review includes the most recent developments in neuroplasticity and other fields related to the treatment of physical therapy, cognitive rehabilitation, pharmacology, newer methods, including neurostimulation, and others. Other topics explored include the influence of time to intervention, injury severity, and other individual variability on neuroplasticity. To emphasize the possibilities of rehabilitation based on neuroplasticity, this paper intends to highlight the gaps not yet tackled, the challenges that abound, and the outlook of the use of neuroplasticity in clinical settings.

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